The primary function of the Platelet-Rich Plasma (PRP) Preparation System is to isolate platelet concentrates from autologous whole blood through centrifugation.
The basic principle is based on the different sedimentation rates of blood components—including white blood cells, red blood cells, and platelets—under centrifugal force. After centrifugation for a defined period, the formed elements of whole blood are separated into distinct layers.
Upon activation, platelets release a variety of growth factors, including TGF-β, PDGF, VEGF-A, EGF, IGF, and bFGF. The functions of these growth factors are as follows:
Growth Factor | Full Name | Primary Functions |
TGF-β | Transforming Growth Factor-β | Plays an important role in inflammatory regulation, tissue repair, and embryonic development. Recognized as a platelet-derived growth factor with beneficial effects during the healing process. |
PDGF | Platelet-Derived Growth Factor | Stimulates osteoblasts to secrete collagen and glycoproteins, contributing to bone matrix formation and mineralization. Promotes cartilage formation and intramembranous ossification. Enhances mitosis, capillary formation, and dermal stromal regeneration. Induces fibroblasts to secrete TGF-β1, supporting wound repair and regeneration. |
VEGF-A | Vascular Endothelial Growth Factor-A | Stimulates endothelial cell proliferation and angiogenesis. Promotes neovascularization and vascular reconstruction at wound sites. Supports endochondral and subperiosteal bone formation. Enhances blood supply to hair follicles and supports hair follicle growth. |
EGF | Epidermal Growth Factor | Promotes epidermal cell proliferation and differentiation. Stimulates fibroblasts to accelerate fibrin and collagen synthesis. Supports granulation tissue formation and helps reduce scar formation during wound healing. |
IGF | Insulin-Like Growth Factor | Induces fibroblast chemotaxis and collagen synthesis. Promotes cartilage matrix formation and supports cell proliferation and differentiation. Contributes to wound repair and tissue regeneration. |
bFGF | Basic Fibroblast Growth Factor | Stimulates fibroblast proliferation, differentiation, and tissue formation, including bone and cartilage. Acts synergistically with VEGF to promote angiogenesis and wound healing. Supports differentiation of hair follicle stem cells. |
1.Simple structure, quick preparation, excellent sealing, and leak-free design.
2.Unique design concentrates platelets in the middle section of the syringe, achieving high platelet enrichment and recovery.
3.Adjustable platelet concentration for easy and convenient operation.
4.Red blood cells fully separated in the lower chamber to minimize contamination.
5.Moderate blood collection volume for optimal efficiency.
Model / Specification | BCM - 100 | BCM - 300 |
Blood Collection Volume | 25–30 mL | 25–30 mL |
PRP Yield / Volume | 10–13 mL | 3–5 mL |
Platelet Enrichment Factor | >1.5× | 4–6× |
Platelet Recovery Rate | ≥80% | ≥60% |
Centrifugation Time | Single spin, 12 min | Double spin, 7 min |
White Blood Cells / WBC | Removal rate up to 71% ± 11% | Recovery Rate: 54% ± 19% |
VEGF-A Enrichment Factor | 3.67 ± 1.30× | 11.196 ± 2.029× |
PDGF-BB Enrichment Factor | 2.918 ± 0.514× | 6.986 ± 2.427× |
TGF-β1 Enrichment Factor | 2.324 ± 0.778× | 3.216 ± 0.885× |
